Jason Calacanis

Angel investor, entrepreneur, and host of This Week in Startups. Jason Calacanis is an early investor in Uber, Robinhood, and other unicorns, sharing startup insights weekly.

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This Week in Startups

This Week in Startups hosted by Jason Calacanis covers startup news, founder interviews, and venture capital insights from Silicon Valley and beyond.

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Top Episodes by Jason Calacanis

1
Mar 27, 2026•10 key insights

The $60 billion resource hiding in space, and the startup trying to mine it | E2268

  • •The $60 billion asteroid hiding 10 million miles away—and how one startup plans to mine it for $10.4M per mission
  • •They use lasers and magnets to extract platinum group metals from space rocks. Here's the wild part: it could have 90...
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2
Mar 26, 2026•10 key insights

This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

  • •This Bittensor subnet could cut drug discovery costs in HALF—turning a $2.6B process into something drastically cheaper
  • •65 billion possible molecules to search through, but miners are finding the best candidates in real-time using AI
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3
Mar 24, 2026•10 key insights

32 Million Dollar Fraud? Delve Scandal | E2266

  • •The $32M Delve fraud scandal: 500 boilerplate compliance reports with identical errors across different companies—bas...
  • •How to spot fraud before you invest: The one question that separates liars from hustlers—and why a 30-minute demo wou...
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4
Mar 21, 2026•10 key insights

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

  • •How a 20-person startup with zero aviation experience convinced Rwanda to let them deliver blood by drone (and it sav...
  • •The 2am call that changed everything: blood delivered to a hospital roof instead of the mailbox—and a nurse had to cl...
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5
Mar 19, 2026•10 key insights

How Robinhood became a $68B company w/ Vlad Tenev

  • •How Vlad pitched investors on a $0 TAM with a $0 revenue model: 'Your TAM is zero and your revenue model is zero'
  • •The brutally stupid answer that almost killed the deal: 'Why do we have to make money?'
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6
Mar 17, 2026•10 key insights

Are Brain-Computer Interfaces Actually Ready for Humans? | E2263

  • •Brain-computer interfaces are finally leaving the lab—Paradromics is implanting their first patients in the next 4-8 ...
  • •The shocking truth about BCIs: micro-wires smaller than human hairs can decode what you're trying to say directly fro...
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7
Mar 14, 2026•10 key insights

This Decentralized Cloud is Thousands of Times Cheaper Than AWS | EP 2262

  • •The surprising reason why decentralized storage is 'thousands of times cheaper' than AWS—and how miners are already p...
  • •They built the first subnet to have its own blockchain—here's why the Bit Tensor ecosystem needed it
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8
Mar 10, 2026•10 key insights

The Global Expansion of Self-Driving Vehicles

  • •The $10M power infrastructure problem nobody's talking about: Getting utilities to provision 3-5 megawatts takes 12-1...
  • •Why Tesla's FSD improved 2X in just 18 months—and why that speed terrifies the industry
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9
Mar 10, 2026•10 key insights

How agents will change banking forever | E2260

  • •How a Shopify CEO just proved AI can improve itself: +19% performance gains in 8 hours with zero ML experience
  • •The shocking reason why AI is now LESS popular than ICE in America—46% of Americans actively oppose it
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10
Mar 7, 2026•10 key insights

Wisdom of the $TAO: the future is decentralized AI

  • •The $100M annual subsidy that's turning stranded talent worldwide into AI millionaires—no VC needed
  • •How a coding co-pilot built for $10M on Bit Tensor is crushing Cursor's $29B valuation at 5-7x cheaper
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Jason Calacanis hosts This Week in Startups. PodPak provides AI-powered summaries of every episode, so you can get the key insights in just 5 minutes.

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Jason Calacanis is known for expertise in Venture Capital, Startups, Technology, Investing. Angel investor, entrepreneur, and host of This Week in Startups. Jason Calacanis is an early investor in Uber, Robinhood, and other unicorns, sharing startup insights weekly.

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