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This Week in Startups
Hosted by Jason Calacanis
This Week in Startups hosted by Jason Calacanis covers startup news, founder interviews, and venture capital insights from Silicon Valley and beyond.
Summary Stats
Episodes Summarized55
Total Insights500
Latest SummaryMar 27, 2026
Part of The Startup Pak
Recent Episode Summaries
Mar 27, 2026•1h 38m•10 insights•5 min read
The $60 billion resource hiding in space, and the startup trying to mine it | E2268
- •The $60 billion asteroid hiding 10 million miles away—and how one startup plans to mine it for $10.4M per mission
- •They use lasers and magnets to extract platinum group metals from space rocks. Here's the wild part: it could have 90% gross margins vs. 14% for Ea...
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Mar 26, 2026•1h 12m•10 insights•5 min read
This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267
- •This Bittensor subnet could cut drug discovery costs in HALF—turning a $2.6B process into something drastically cheaper
- •65 billion possible molecules to search through, but miners are finding the best candidates in real-time using AI
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Mar 24, 2026•1h 26m•10 insights•5 min read
32 Million Dollar Fraud? Delve Scandal | E2266
- •The $32M Delve fraud scandal: 500 boilerplate compliance reports with identical errors across different companies—basically 'copy-paste with logo s...
- •How to spot fraud before you invest: The one question that separates liars from hustlers—and why a 30-minute demo would've caught Delve immediately
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Mar 21, 2026•1h 37m•10 insights•5 min read
The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265
- •How a 20-person startup with zero aviation experience convinced Rwanda to let them deliver blood by drone (and it saved 51% of maternal deaths)
- •The 2am call that changed everything: blood delivered to a hospital roof instead of the mailbox—and a nurse had to climb up a dangerous rooftop to ...
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Mar 19, 2026•49m•10 insights•5 min read
How Robinhood became a $68B company w/ Vlad Tenev
- •How Vlad pitched investors on a $0 TAM with a $0 revenue model: 'Your TAM is zero and your revenue model is zero'
- •The brutally stupid answer that almost killed the deal: 'Why do we have to make money?'
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